Familial Clustering Identified in Primary Hyperparathyroidism

Familial Clustering in Primary Hyperparathyroidism

Research has identified familial clustering in primary hyperparathyroidism, with first-degree relatives at a higher risk than control patients.

First-degree relatives of patients with primary hyperparathyroidism are at greater risk of having the condition themselves.

Prior studies have suggested a link between primary hyperparathyroidism and an elevated risk for malignancy, with a pooled prevalence of 20% for any type of cancer among this population.

A link to cancer risk among parents, siblings, and children is less certain.

Author's summary: Familial clustering found in primary hyperparathyroidism.

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Rheumatology Advisor Rheumatology Advisor — 2025-10-30

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