Ebola produces serious hemorrhagic fever with elevated fatality. Transmission occurs mostly via hands-on contact infectious fluids of infected individuals. The virus is native in certain regions of Africa, as outbreaks often occurring in rural areas. Notable epidemics include West Africa’s 2014-2016 epidemic, impacting Guinea, Liberia, and Sierra Leone. The 2020 outbreak was in 2020 in the Democratic Republic of Congo. Clinical signs usually emerge in 2-21 days after exposure, with high fever, vomiting, watery diarrhea, and abdominal pain. Present treatments use care that supports, like fluid therapy and management of complications, together with trials and vaccines.